Ajeng Maulidya Nur, Ika Azdah Murnita, Adriandy Saleh

Hal-Hal Yang Ada Hubungan Dengan Kanker Payudara Pada Penderita Di Beberapa Lokasi Di Wilayah Asia, Eropa Periode Tahun 2010 Sampai Dengan Tahun 2021

Introduction

Hal-hal yang ada hubungan dengan kanker payudara pada penderita di beberapa lokasi di wilayah asia, eropa periode tahun 2010 sampai dengan tahun 2021. Temukan faktor-faktor risiko penting terkait kanker payudara di Asia & Eropa (2010-2021): riwayat keluarga, usia, kontrasepsi, obesitas, dan alkohol.

Abstract

Breast cancer is a disease in which cells in the breast tissue change and divide uncontrollably and form lumps or masses, generally affecting women and mostly starting in the lobules (mammary glands) or in the ducts that connect the lobules to the nipple. The purpose of this study was to find out things that related with breast cancer there were family history of breast cancer, age at first menstruation, menopausal status, age at first childbearing, hormonal contraception, obesity, alcohol. The reasearch method was descriptive using literature objective approach on matters related to breast cancer in the journal of medical research in the literature. The results of the twenty studies analyzed showed that things that were related to breast cancer in several locations in Asia, Europe for the period 2010 to 2021, there were family history of breast cancer (p-value = <0.001), age at first menstruation (p-value = <0.001), menopausal status (p-value = <0.001), age at first childbearing (p-value = 0.002), hormonal contraception (p-value = <0.001), obesity (p-value = <0.001), alcohol (p-value = 0.006), had a significant relationship to breast cancer in several locations in Asia, Europe for the period 2010 to 2021. This research hoped to be used as an additional information for improving the role of health workers for prevent and handle the breast cancer.

Review

This manuscript, titled "Hal-Hal Yang Ada Hubungan Dengan Kanker Payudara Pada Penderita Di Beberapa Lokasi Di Wilayah Asia, Eropa Periode Tahun 2010 Sampai Dengan Tahun 2021," aims to identify factors associated with breast cancer among patients in Asia and Europe between 2010 and 2021. The abstract describes a descriptive research method using a "literature objective approach" to review medical research journals. The core findings indicate a statistically significant relationship between breast cancer and several well-known risk factors, including family history, age at first menstruation, menopausal status, age at first childbearing, hormonal contraception, obesity, and alcohol consumption, all with highly significant p-values. While the topic is undeniably important given the global burden of breast cancer, the abstract raises several questions regarding methodological rigor and the novelty of its contribution. The paper addresses a highly relevant public health issue by focusing on breast cancer risk factors, a topic of continuous importance for prevention and early detection strategies. The broad geographical scope encompassing Asia and and Europe, along with the extensive time period (2010-2021), suggests an ambitious attempt to synthesize a significant body of literature. The identification of a comprehensive list of factors, all showing strong statistical associations, reinforces existing knowledge and could serve as a consolidated reference point for those seeking an overview of these established determinants within the specified regions and timeframe. The stated aim of providing additional information for health workers to improve breast cancer prevention and handling is a commendable objective. Despite the relevance of the topic, the abstract lacks critical detail regarding the methodology, which significantly impacts the interpretability and validity of the results. Describing the method as "descriptive using literature objective approach on matters related to breast cancer in the journal of medical research in the literature" is insufficient. It is unclear if this is a systematic review, a scoping review, or a narrative review; without explicit details on search strategy, inclusion/exclusion criteria for studies, quality assessment, and data synthesis methods, the robustness of the findings cannot be ascertained. Furthermore, while p-values are provided, the absence of effect sizes (e.g., odds ratios, hazard ratios, or relative risks) makes it impossible to gauge the magnitude or direction of the associations, which is crucial for clinical and public health implications. Given that the identified risk factors are widely recognized in the literature, the abstract does not clearly articulate the unique contribution or novel insights this specific review offers beyond a reaffirmation of established knowledge. Clarifying these methodological aspects and emphasizing the distinctive contribution would substantially strengthen the manuscript.

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