Retno Pudji Rahayu, Sri Wigati Mardi Mulyani, Ristya Sylva Imannia, Jefferson Caesario, Dyta Loverita, Elvin Nuzulistina

ANTI-INFLAMMATORY POTENTIAL OF FUNGUS COMBS FROM INDO-MALAYAN TERMITE MACROTERMES GILVUS HAGEN MOUND: REVIEW ARTICLE

Introduction

Anti-inflammatory potential of fungus combs from indo-malayan termite macrotermes gilvus hagen mound: review article. Explore the anti-inflammatory potential of fungus combs from Indo-Malayan Macrotermes gilvus Hagen termite mounds. Discover bioactive components that enhance immunity & may reduce chronic disorders.

Abstract

There is evidence that termite colonies of the subfamily Termitomyces produce an unusual structure called a fungus comb, especially Termite mounds in Indo-Malaysian regions. This comb may include bioactive components that the termites use to investigate if they might aid in the body's inflammatory response. The anti-inflammatory potential, concentration, and bioavailability of fungal comb from the Indo-Malayan termite macrotermes gilvus Hagen mound will be further discussed in this research. We utilized databases to review the current evidence related to anti-inflammatory potential of fungus combs and termite macrotermes gilvus hagen mound. We discussed the most recent evidence of fungus combs and termite macrotermes gilvus mound regarding the anti-inflammatory potential, concentration, and bioavailability. This study concludes that ethyl acetate extract from fungus comb could enhance the immune system. Phenolic compounds have a positive effect on health indicators. These mechanisms may account for the decreased prevalence of chronic degenerative disorders in populations.

Review

This review article proposes to explore the anti-inflammatory potential of fungus combs derived from the Indo-Malayan termite *Macrotermes gilvus Hagen* mound, a fascinating and underexplored natural resource. The topic is highly relevant given the growing interest in natural product discovery for therapeutic applications, particularly in the realm of anti-inflammatory agents. Focusing on a specific biological interaction within termite colonies provides a unique angle for investigation into novel bioactive compounds. The abstract clearly outlines the review's intent to discuss the anti-inflammatory potential, concentration, and bioavailability of these fungus combs. The methodology states a reliance on database reviews to synthesize current evidence, which is appropriate for this type of article. The reported conclusions highlight specific findings from the literature, such as the potential of ethyl acetate extracts to enhance the immune system and the beneficial effects of phenolic compounds, suggesting a mechanistic understanding of their health benefits, including a decreased prevalence of chronic degenerative disorders. While the subject matter is compelling, the abstract could benefit from greater detail regarding the specific scope and depth of the evidence review. For instance, it would be valuable to indicate whether the 'discussion' of anti-inflammatory potential includes *in vitro*, *in vivo*, or epidemiological studies. Furthermore, the strong concluding statements about immune system enhancement and decreased chronic disease prevalence, while potentially supported by the reviewed literature, might be more appropriately framed as 'evidence suggests' or 'the literature points towards' in an abstract to reflect the nature of a review rather than a primary research paper. The full article should therefore meticulously detail the criteria for evidence selection and the critical appraisal process used to arrive at these significant conclusions.

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