Research Results in Pharmacology

0.0 (0 ratings)

Pharmacy

22 views

Research Results in Pharmacology is a peer-reviewed, open access, rapidly published journal covering various aspects of pharmacology. The Journal publishes articles devoted to molecular screening with the use of modern methods of proteomics, cellular technologies, results of experimental studies in modeling abnormalities in laboratory animals and clinical studies in the field of pharmacotherapy, pharmacokinetics, pharmacoepidemiology, personalized therapy, multicenter studies and evidence-based medicine.

Articles in this Journal

Nonclassical cardiovascular effects of imidazoline receptor agonists

Introduction: Imidazoline receptors are a group of metabotropic receptors whose activation is associated with changes in a number of functional parameters, including hemodynamics (lowering blood pressure (BP), negative chrono-and inotropic effects),...

View Full Research

Assessment of physiological parameters in the application of a double adeno-associated virus 9 with a codon-optimized DYSF gene for limb girdle muscular dystrophy type R2

Introduction: Gene therapy for Myoshi myopathy is extremely relevant, as it may become the first pathogenetic treatment for dysferlinopathy. The aim of this study was to study the efficacy and safety of the use of a genetic construct, the AAV9-DYSF-D...

View Full Research

Cardiotropic medicinal products of plant origin. Prospects for use in modern clinical practice

Introduction: The aim of the research was to study the current state of use and improvement of the prospects for the using cardiological medicinal products obtained on the basis of medicinal plant raw materials. Materials and Methods: The work used c...

View Full Research

Correction of protein and lipid spectra of erythrocyte membranes as a pathogenetic supplement to the therapy of coronary heart disease

Introduction: Coronary heart disease is currently a pressing problem in the medical and scientific community. The hemic component, which is a disruption of the ability of red blood cells to effectively exchange gases, is of great importance in ischem...

View Full Research

The effect of acute swimming stress, corticosterone, dexamethasone, and fludrocortisone on anxiety-like behavior in mice

Introduction: Acute swimming stress (ASS) exerts a biphasic effect on anxiety-like behavior (ALB) in mice, inducing an enhancement and a subsequent decrease in ALB 1 h and 24 h after exposure, respectively. Presumably, this effect may be caused by th...

View Full Research

Comparison of CD-1 and ICR mouse strains for impulsivity in the enriched cross-maze test: Effects of atomoxetine

Introduction: Attention deficit hyperactivity disorder (ADHD) in children and adults is a neuropsychiatric condition that is characterized by difficulty sustaining attention and behavioral impulsivity. It is one of the problems of modern medicine req...

View Full Research

Orthogonal approach and critical quality attributes for gene and cell therapy products

Introduction: Gene and cell therapy (GCT) products are revolutionizing medicine because they are made up of unique biological components like genetic material, viral vectors, and viable cells. However, their complexity necessitates rigorous quality...

View Full Research

Adherence to dual antiplatelet therapy among outpatients after acute myocardial infarction in primary care

Introduction: The efficacy outcomes of dual antiplatelet therapy (DAPT) observed in randomized controlled trials are often not replicated in real-world post-myocardial infarction (MI) patients due to suboptimal adherence to prescribed pharmacotherapy...

View Full Research

Anxiolytic, antidepressant and analgesic activities of novel derivatives of 1-(3-phenylpyrrol-2-yl)-1,3-dihydro-2H-benzimidazol-2-one

Introduction: Benzimidazole (1,3-benzodiazole) derivatives hold an important place in the field of medicinal chemistry, since they have a wide spectrum of pharmacological activity, as well as high variability of the mechanisms of action: GABA-, serot...

View Full Research

Regulation of 11β-hydroxysteroid dehydrogenase isoforms – novel drug targets for osteoporosis therapy

Introduction: Osteoporosis is an significant medical and social public health problem in an aging or elderly society, the issue of pharmacological correction of which remains unresolved to this day. Materials and Methods: The rationale for this idea...