Proceedings of IMPRS

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Explore the scientific proceedings of the International Max Planck Research School (IMPRS). Discover cutting-edge research, academic papers, and key findings.

Articles in this Journal

Derivation of a Multivariable Model to Assist Emergency Department Triage of Heart Failure Patients by Their Diuretic Treatment Needs

Background: Emergency medicine physicians (EMP) treat 1 million patients with acute decompensated heart failure (ADHF) annually. After emergency department (ED) treatment, EMPs must determine the need for further intravenous loop diuretic (IVLD) ther...

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Long Term Effects of Transient Romidepsin Exposure on Osteosarcoma Sarcospheres

Background:Osteosarcoma, the most prevalent primary bone cancer, disproportionally affects adolescents and young adults. Despite aggressive chemotherapeutics, prognosis remains poor, highlighting the need for novel therapeutics. Romidepsin, a histone...

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Exploring the Impact of Plasmin Inhibitors on Clotting Characteristics as a Novel Therapeutic for Thromboembolic Events

Background:Thromboembolisms are common, life-threatening emergencies. Systemic hemorrhaging post-thrombolytic treatment is an adverse reaction, highlighting the need for safer clot-digesting therapeutics. Our research focuses on an endogenous fibrino...

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The Role of Cross-linked Actin Networks in the Proliferation and Senescence of Primary Human Trabecular Meshwork Cells

Purpose: TGFβ2 has been found to be elevated in the trabecular meshwork (TM) of patients with primary open-angle glaucoma. TM cells treated with TGFβ2 form cross-linked actin networks (CLANs). These CLANs are a restructuring of the cells’ actin cytos...

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Clinical Impact and Sustainability of a Standardized Neonatal Nephrology Consult Program

Background/Objective: Acute kidney injury (AKI) is common in high-risk neonates and is associated with increased morbidity and mortality. Standardized programs to identify AKI exist only in a few institutions. The sustainability and clinical impact o...

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Determining the Therapeutic Effect of Human Neuritin 1 on the Restoration of Degenerated Retinal Ganglion Cells from Glaucoma Patients

Background and Hypothesis: Glaucoma is a group of optic neuropathies that affects approximately 76 million people worldwide. The main risk factor is elevated intraocular pressure (IOP) which predominantly affects retinal ganglion cells (RGC), resulti...

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Evaluation of Resident Presentations Using a DEI Checklist

Background: In 2021, the Indiana University School of Medicine Department of Emergency Medicine developed a DEI checklist for residents presenting to their colleagues during weekly didactic sessions. The purpose of this present study is to evaluate t...