Sadia Iqbal, Syeda Azka Sajid, Muhammad Ali, Noor Mushtaq, Muhammad Wasif Sultan, Mehvish Mushtaq, Tehreem Tahir, Javaria Mohsin, Iqra Shafiq, Usman Muzaffar

Techniques for Detection of Trichothecene in Food: A Comprehensive Review

Introduction

Techniques for detection of trichothecene in food: a comprehensive review. Comprehensive review on trichothecene detection techniques in food. Explores health risks, management strategies, and impact on food safety, public policy, and security.

Abstract

Trichothecenes, pose significant health risks to humans and animals by contaminating food and feed. These toxins are classified into Type A and Type B. Type A trichothecenes are commonly detected in various food matrices, while Type B trichothecenes contaminate crops and are linked to alimentary toxicities, including emetic reactions. Advanced detection methods such as liquid chromatography-tandem mass spectrometry are widely used. Biological controls, such as Debaryomyces hansenii, have shown promise, reducing toxin content and suppressing pathogen spread. Trichothecenes exhibit ribotoxic, pro-inflammatory, and cytotoxic effects, making their management a critical focus in food safety. This review comprehensively explores detection techniques, management strategies, and the impact of trichothecene contamination on human health, emphasizing its relevance in public policy and food security.

Review

The review titled "Techniques for Detection of Trichothecene in Food: A Comprehensive Review" addresses a highly pertinent and critical area within food safety and public health. Trichothecenes represent a significant global challenge due to their widespread contamination of food and feed and their serious toxicological profiles. The abstract effectively lays out a broad scope, promising a thorough examination of detection methods, management strategies, and the intricate health impacts of these mycotoxins, underscoring the necessity of such a comprehensive overview in the current scientific landscape. A key strength indicated by the abstract is its intention to provide a holistic perspective. It judiciously categorizes trichothecenes into Type A and Type B, linking them to specific food matrices and alimentary toxicities, which is crucial for targeted analysis and mitigation. The inclusion of advanced analytical techniques like liquid chromatography-tandem mass spectrometry highlights the cutting-edge methodologies in detection, while also incorporating promising biological control measures such as *Debaryomyces hansenii*. Furthermore, the abstract correctly emphasizes the severe ribotoxic, pro-inflammatory, and cytotoxic effects, framing the issue within a robust toxicological context. The ambition to connect these scientific and technological discussions to broader implications in public policy and food security is particularly commendable and vital. Such a comprehensive synthesis would serve as an invaluable resource for researchers, regulators, and policymakers alike, facilitating informed decision-making and the development of more effective strategies to combat trichothecene contamination. This review, as outlined, promises to consolidate disparate information into a coherent narrative, thereby significantly contributing to the ongoing efforts to safeguard human and animal health from these pervasive mycotoxins.

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