Medine Sibel KARAĞAÇ, Hamid CEYLAN

Effects of Natural Polyphenols Against Skin Aging

Introduction

Effects of natural polyphenols against skin aging. Natural polyphenols combat skin aging and age-related issues. Explore their antioxidant mechanisms for effective prevention strategies and enhanced well-being.

Abstract

Aging is a natural process in humans that causes changes in the immune response, increased frailty and malignancy, and reduced skin elasticity. The ever-increasing global average age significantly affects the economic structure of countries by increasing expenditures on health and other social activities to ensure individual welfare. Therefore, it is important to determine the mechanisms of action of environmental factors that cause health problems that have negative effects on quality of life at the molecular level in order to determine effective treatment and prevention strategies. Interest in the use of natural products in the battle against age-related neurological and dermatological asthma has recently increased. Polyphenols are natural products that show many beneficial biological activities when taken into the body in appropriate amounts. Regular intake of polyphenols from food and beverages shows antioxidant, anticarcinogenic, antimutagenic, antitumor, antiobesogenic, antimicrobial, neuroprotective, and cardioprotective effects. At the same time, polyphenols have a high potential for the prevention of agerelated dermatological problems, and therefore further studies on dietary polyphenols are important to better understand these protective effects.

Review

This paper, titled "Effects of Natural Polyphenols Against Skin Aging," addresses a highly relevant and timely topic given the global demographic shift towards an aging population and the associated socio-economic and individual health burdens. The abstract effectively highlights the multifactorial nature of aging, including its impact on skin elasticity, and underscores the critical need for effective preventive and therapeutic strategies. The focus on natural products, specifically polyphenols, aligns with a growing interest in sustainable and biologically friendly interventions for age-related conditions. The abstract provides a compelling rationale for investigating polyphenols, detailing their wide array of established beneficial biological activities, such as antioxidant, anticarcinogenic, and neuroprotective effects. It convincingly argues for their high potential in preventing age-related dermatological problems, thereby positioning them as a promising avenue for research in skin aging. The mention of "regular intake from food and beverages" also hints at a practical and accessible approach to prevention, adding to the immediate relevance of the topic. The overall scope of the work appears to be a comprehensive overview or review of the existing knowledge regarding polyphenols' role in combating skin aging. While the abstract successfully establishes the importance of the topic and the potential of polyphenols, it currently functions more as an extended introduction to a review article rather than a concise summary of specific findings or methodologies from a particular study. It broadly discusses the *potential* and *importance* of further studies but does not provide any concrete details about the methods employed, specific polyphenols investigated, key results obtained, or the precise mechanisms elucidated by *this* particular paper. To be more impactful and informative for a research audience, a full paper stemming from this abstract would ideally need to delve into specific experimental designs, *in vitro* or *in vivo* data, identified molecular pathways, or comparative analyses of different polyphenols to truly advance the understanding of their effects against skin aging.

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