Ni'ma Ainul Fuadi, St Aisyah Sijid

Patofisiologi penyakit pada berbagai sistem organ manusia

Introduction

Patofisiologi penyakit pada berbagai sistem organ manusia. Pelajari patofisiologi penyakit pada sistem organ manusia, dari kegagalan pertahanan tubuh hingga infeksi (virus, bakteri), autoimun, kardiovaskular, endokrin, dan keganasan. Pahami patogen.

Abstract

Sistem pertahanan tubuh yang gagal melawan agen infeksi akan menyebabkan patogen tersebut dapat tubuh dan berkembang di dalam tubuh, kemudian mengganggu sistem fisiologis tubuh yang telah tersusun secara sistematik. Kegagalan tersebut menimbulkan terjadinya penyakit bagi tubuh. Penyakit umumnya menyebabkan nyeri yang terjadi dari adanya jaringan dan organ tubuh yang rusak dan terganggu fungsi kerjanya. Patofisiologi berbagai penyakit yang menyerang sistem organ manusia, seperti penyakit penyebab infeksi (sifilis), autoimun (sistemik lupus eritomatosus), kardiovaskuler (kardiomiospati dilatasi), endokrin (diabetes melitus), keganasan (leukimia), dan sistem reproduksi (penyakit infeksi menular seksual). Penyakit-penyakit tersebut disebabkan oleh mikroorganisme patogen. Patogen merupakan agen infeksi yang membawa zat asing atau antigen ke dalam tubuh melalui berbagai transmisi. Patogen penyebab infeksi berasal dari mikroorganisme seperti virus, bakteri, fungi, dan protista.

Review

The title "Patofisiologi penyakit pada berbagai sistem organ manusia" suggests a comprehensive review of disease mechanisms affecting various human organ systems. The abstract introduces disease as a consequence of the immune system's failure against infectious agents, leading to physiological disruption and pain from tissue damage. It aims to cover a broad spectrum of diseases, listing examples such as syphilis (infectious), systemic lupus erythematosus (autoimmune), dilated cardiomyopathy (cardiovascular), diabetes mellitus (endocrine), leukemia (malignancy), and sexually transmitted infections (reproductive system). The ambition to encompass such a wide range of conditions and their underlying pathophysiology is substantial, touching upon fundamental aspects of medical science. A significant concern, however, arises from a critical factual inaccuracy within the abstract. It explicitly states: "Penyakit-penyakit tersebut disebabkan oleh mikroorganisme patogen." This is incorrect for several of the listed examples; Systemic Lupus Erythematosus is an autoimmune condition, Dilated Cardiomyopathy often has genetic or idiopathic causes, Diabetes Mellitus is a metabolic/autoimmune disorder, and Leukemia is a malignancy—none of which are primarily caused by pathogenic microorganisms. This fundamental error immediately undermines the scientific credibility of the abstract. Furthermore, the abstract is predominantly descriptive and lacks specific objectives, methodologies, or an indication of novel insights or a particular depth of analysis that would be expected from a journal article. It reads more like a general introductory paragraph to a vast medical topic rather than a summary of a focused research or comprehensive review. While the topic of pathophysiology across organ systems is undeniably crucial and warrants thorough scientific exploration, the current abstract requires substantial and immediate revision. The factual error regarding disease etiologies must be rectified as a priority. To be considered a viable contribution to a scientific journal, the authors must clearly define the scope, specific objectives, and the methodological approach of their work. Is this intended as a comprehensive review of existing literature, a conceptual paper proposing new frameworks, or a synthesis of recent advancements? As it stands, the abstract merely lists broad categories without indicating the depth, unique perspective, or specific arguments the full paper intends to present. Significant restructuring and clarification are essential to elevate this from a general introductory text to a publishable scientific abstract.

Full Text

Comments

You need to be logged in to post a comment.